Table 3.
Secondary analysis of the effects of low-fat and low-carbohydrate diets on serum adipokine concentrations among women who were adherent to the dietary component of the intervention, N = 18
| Biomarker | Intervention arm | Baseline | Week 34 | Week 52 |
|---|---|---|---|---|
| Geometric mean (95% CI) | Geometric mean (95% CI) | Geometric mean (95% CI) | ||
| Low-fat | 11.93 (8.13–17.50) | 10.11 (7.02–14.57) | 8.39 (4.85–14.53) | |
| Adiponectin (μg/mL) | Low-carbohydrate | 11.06 (7.53–16.25) | 11.55 (8.20–16.27) | 12.11 (7.69–19.09) |
| Overall | 11.49 (8.76–15.07) | 10.80 (8.41–13.88) | 10.08 (7.06–14.40) | |
| Leptin (ng/mL) | Low-fat | 28.21 (16.76–47.50) | 22.21 (12.80–38.54) | 22.97 (7.95–66.37) |
| Low-carbohydrate | 29.12 (17.24–49.18) | 25.34 (14.92–43.04) | 20.36 (9.41–44.06) | |
| Overall | 28.66 (19.81–41.48) | 24.65 (16.00–37.97) | 21.62 (11.23–41.65) | |
| A/L ratio | Low-fat | 0.43 (0.23–0.80) | 0.42 (0.23–0.76) | 0.41 (0.16–1.06) |
| Low-carbohydrate | 0.38 (0.20–0.71) | 0.46 (0.27–0.80) | 0.58 (0.27–1.25) | |
| Overall | 0.40 (0.26–0.63) | 0.44 (0.29–0.66) | 0.49 (0.27–0.90) |
NOTE: Mixed models with repeated measurements of natural log transformed serum adipokine concentrations were used. Overall estimates are averages across the two diets. Estimates for leptin assume a quadratic trend in time. All other estimates assume a linear trend in time. Data presented correspond to geometric means and 95% CIs. No difference in trend by diet was observed for any biomarker.