Table 3.
Parameter | SVR | Non-SVR | P value |
(n = 11) | (n = 33) | ||
Center: | |||
CUPH | 1 (9) | 9 (27.3) | 0.330 |
YAGCC | 5 (45.5) | 13 (39.4) | |
NLI | 5 (45.5) | 11 (33.3) | |
Age (yr) | 9.9 ± 3.76 | 10.39 ± 3.45 | 0.385 |
Male | 9 (81.8) | 22 (66.7) | 0.340 |
Expected duration of infection (yr) | 3.77 ± 3.28 | 5.61 ± 4.02 | 0.341 |
Previous treatment trial | 2 (18.2) | 9 (27.3) | 0.546 |
Previous treatment type2 | |||
Short-acting IFN + RBV | 2 (100) | 8 (88.9) | 1.000 |
PEG-IFN + RBV | 0 (0) | 1 (11.1) | |
Previous response type2 | |||
Non-responder | 0 (0) | 7 (77.8) | 0.0391 |
Relapser | 2 (100) | 2 (22.2) | |
Possible cause of infection | |||
Surgery | 4 (36.4) | 10 (30.3) | 0.709 |
Blood transfusion | 4 (36.4) | 11 (33.3) | 0.854 |
Tonsillectomy | 1 (9.1) | 4 (12.1) | 0.784 |
Circumcision | 9 (81.8) | 22 (66.7) | 0.340 |
Minor procedures | 8 (72.7) | 22 (66.7) | 0.709 |
Vertical transmission | 2 (18.2) | 6 (18.2) | 1.000 |
Family contact | 4 (36.4) | 14 (42.4) | 0.723 |
Injection interval: | |||
5 d | 1 (9) | 16 (48.5) | 0.0201 |
7 d | 10 (91) | 17 (51.5) | |
Treatment duration: | |||
48 wk | 9 (81.8) | 27 (81.8) | 0.940 |
72 wk | 2 (18.2) | 6 (18.2) | |
Genotype: | |||
4a | 4 (80) | 24 (77.4) | 0.890 |
4b | 1 (20) | 7 (22.6) | |
Viral load: | |||
Low | 7 (64) | 11 (33.4) | 0.180 |
Moderate | 4 (36) | 20 (60.6) | |
High | 0 (0) | 2 (6.0) | |
Histological Activity: | |||
Mild | 11 (100) | 31 (96.9) | 0.550 |
Moderate | 0 (0) | 1 (3.1) | |
Fibrosis stage: | |||
No | 1 (9.1) | 12 (37.5) | 0.112 |
Mild | 10 (90.9) | 18 (56.3) | |
Moderate | 0 (0) | 2 (6.3) | |
Steatosis: | |||
No | 11 (100) | 28 (87.5) | 0.460 |
Mild | 0 (0) | 3 (9.4) | |
Moderate | 0 (0) | 1 (3.1) |
Significant;
Percentages were calculated for those with previous treatment trial. SVR: Sustained virological response.