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. 2014 Apr 28;20(16):4723–4729. doi: 10.3748/wjg.v20.i16.4723

Table 5.

Sensitivity and specificity of gene sets for hepatitis B virus (+) hepatocellular carcinoma detection in chronic hepatitis B group

No. Marker TP/FN FP/TN Sensitivity (%)TP/(TP + FN) Specificity (%)TN/(TN + FP)
1 AFP 56/44 14/23 56.0 62.1
2 MT1M 50/50 2/35 50.0 94.6
3 MT1G 69/31 6/31 69.0 83.8
4 MT1M/MT1G 90/10 7/30 90.0 81.1

Sensitivity (%), TP/(TP + FN) and specificity (%), TN/(TN + FP) of each gene set were calculated and plotted. MT1M/MT1G, MT1M or MT1G promoter methylation. TP: True positive; FN: False negative; FP: False positive; TN: True negative.