Table 3.
Distribution of genotype and allele frequencies of mutations in Crohn’s disease and ulcerative colitis patients compared with healthy controls in the Guangxi Zhuang population n (%)
| Mutant | Genotype | Allele | Control |
CD |
UC |
||
| P value | P value | ||||||
| P268S | aP1 | NS1 | |||||
| CC | 71 (98.6) | 42 (87.5) | 54 (100.0) | ||||
| CT | 1 (1.4) | 6 (12.5) | 0 (0.0) | ||||
| TT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| T | 1 (0.7) | 6 (6.2) | cP2 | 0 (0.0) | NS2 | ||
| JW1 | NS1 | NS1 | |||||
| CC | 72 (100.0) | 48 (100.0) | 54 (100.0) | ||||
| CT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| TT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| T | 0 (0.0) | 0 (0.0) | NS2 | 0 (0.0) | NS2 | ||
| N852S | NS1 | NS1 | |||||
| AA | 72 (100.0) | 48 (100.0) | 54 (100.0) | ||||
| AG | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| GG | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| G | 0 (0.0) | 0 (0.0) | NS2 | 0 (0.0) | NS2 | ||
Comparisons of genotype frequencies;
Comparisons of allele frequencies.
P < 0.05 vs control using Fisher's exact test;
P < 0.05 vs control using Fisher's exact test. CD: Crohn’s disease; UC: Ulcerative colitis; NS: No significance.