Table 4.
Distribution of genotype and allele frequencies of mutations in Crohn’s disease and ulcerative colitis patients compared with healthy controls in the Guangxi Han population n (%)
| Mutant | Genotype | Allele | Control |
CD |
UC |
||
| P value | P value | ||||||
| P268S | bP1 | NS1 | |||||
| CC | 78 (100.0) | 46 (92.0) | 48 (96.0) | ||||
| CT | 0 (0.0) | 4 (8.0) | 2 (4.0) | ||||
| TT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| T | 0 (0.0) | 4 (4.0) | dP2 | 2 (2.0) | NS2 | ||
| JW1 | NS1 | NS1 | |||||
| CC | 78 (100.0) | 50 (100.0) | 50 (100.0) | ||||
| CT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| TT | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| T | 0 (0.0) | 0 (0.0) | NS2 | 0 (0.0) | NS2 | ||
| N852S | NS1 | NS1 | |||||
| AA | 78 (100.0) | 50 (100.0) | 50 (100.0) | ||||
| AG | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| GG | 0 (0.0) | 0 (0.0) | 0 (0.0) | ||||
| G | 0 (0.0) | 0 (0.0) | NS2 | 0 (0.0) | NS2 | ||
Comparisons of genotype frequencies;
Comparisons of allele frequencies.
P < 0.05 vs control using Fisher's exact test;
P < 0.05 vs control using Fisher's exact test. CD: Crohn’s disease; UC: Ulcerative colitis; NS: No significance.