Table 5.
Clinical characteristics of Crohn’s disease patients in Guangxi with and without P268S mutations
| Phenotype | n | P268S+ | P268S- | P value |
| Age of onset | aP | |||
| ≤ 40 years | 45 | 8 (17.8) | 37 (82.2) | |
| > 40 years | 53 | 2 (3.8) | 51 (96.2) | |
| Location | NS | |||
| Ileum | 58 | 6 (10.3) | 52 (89.7) | |
| Colon/ileocolon | 40 | 4 (10.0) | 36 (90.0) | |
| Gender | NS | |||
| Male | 51 | 7 (13.7) | 44 (86.3) | |
| Female | 47 | 3 (6.4) | 44 (93.6) | |
| Ethnic groups | NS | |||
| Han | 50 | 4 (8.0) | 46 (92.0) | |
| Zhuang | 48 | 6 (12.5) | 42 (87.5) | |
| Comorbidities | NS | |||
| Luminal stenosis | 31 | 4 (12.9) | 27 (87.1) | |
| No luminal stenosis | 67 | 6 (9.0) | 61 (91.0) | |
| Severity | NS | |||
| Severe | 42 | 3 (7.1) | 39 (92.9) | |
| Mild-moderate | 56 | 7 (12.5) | 49 (87.5) |
NS: No significance. P268S+ Mutant P268S; P268S- Wild-type P268S.
a
P < 0.05 using Fisher's exact test.