Table 2.
Performance of point shear wave elastography (n = 98) and transient elastography (n = 101) in patients with chronic hepatitis C
| Parameter | Method | F ≥ 2 | F ≥ 3 | F = 4 |
| Cut-off in kPa | PSWE | 5.7 | 5.8 | 7.2 |
| TE | 6.9 | 7.3 | 9.3 | |
| AUC | PSWE | 0.80 (0.71-0.87) | 0.88 (0.80-0.94) | 0.95 (0.89-0.99) |
| TE | 0.82 (0.73-0.89) | 0.95 (0.88-0.98) | 0.92 (0.85-0.97) | |
| Sensitivity % | PSWE | 62.0 (47.2-75.3) | 85.2 (66.3-95.8) | 90.0 (55.5-99.7) |
| TE | 62.7 (48.1-75.9) | 89.9 (70.8-97.6) | 90.0 (55.5-99.7) | |
| Specificity % | PSWE | 91.7 (80.0-97.7) | 84.5 (74.0-92.0) | 88.6 (80.1-94.4) |
| TE | 83.7 (70.3-92.7) | 80.8 (69.9-89.1) | 87.8 (79.2-93.7) | |
| PPV % | PSWE | 88.6 (73.3-96.8) | 67.6 (49.5-82.6) | 47.4 (24.4-71.1) |
| TE | 80.0 (64.1-91.1) | 63.2 (45.7-78.4) | 45.0 (23.1-78.5) | |
| NPV % | PSWE | 69.8 (57.0-80.8) | 93.7 (84.7-98.3) | 98.7 (93.1-100) |
| TE | 68.3 (55.0-79.7) | 95.2 (86.5-99.0) | 98.7 (93.2-100) | |
| +LR | PSWE | 7.4 (2.8-19.5) | 5.5 (3.1-9.7) | 7.9 (4.3-14.7) |
| TE | 3.8 (2.0-7.5) | 4.6 (2.8-7.6) | 7.4 (4.1-13.3) | |
| -LR | PSWE | 0.4 (0.3-0.6) | 0.2 (0.07-0.4) | 0.1 (0.02-0.7) |
| TE | 0.4 (0.3-0.6) | 0.1 (0.05-0.4) | 0.1 (0.02-0.7) |
In parentheses: 95%CI. PSWE: Point shear wave elastography; TE: Transient elastography; kPa: Kilopascals; AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; +LR: Positive likelihood ratio; -LR: Negative likelihood ratio.