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. Author manuscript; available in PMC: 2014 Apr 26.
Published in final edited form as: J Hypertens. 2013 Nov;31(11):2270–2281. doi: 10.1097/HJH.0b013e3283649b33

Figure 5. In Ang-II-induced renal remodeling, elastin degradation and wall-to-lumen ratio is increased in TIMP2-/- mice.

Figure 5

Figure 5

Kidney sections were stained with Van Gieson’s stain and dark grey/black color depicts elastin (a-d). Bar diagram (e) represents the total elastin area against the background presented as mean percent change ± SEM (n=6/group) using WT + Saline as control. Ang-II, angiotensin; TIMP, tissue inhibitor of metalloproteinase; WT, wild-type. *p < 0.05 vs. WT + Ang-II; †p < 0.05 vs. WT + saline; and p < 0.009 vs. TIMP2-/- + saline. Bar diagram (f) represents the wall- to-lumen ratio of interlobular arteries in the cortex, *p < 0.05 vs. WT + Ang-II; p = 0.004 vs. WT + saline, p = 0.01 vs.TIMP2-/- + saline. Original image, × 20 magnification.

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