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Comparison of Normalized index of methylation (NIM) for the tumor suppressor genes. a Between normal bladder mucosa (NB) and muscle invasive high grade (IHG) urothelial bladder cancer (*p-value for APC and MGMT was <0.001) b Between muscle invasive high grade (IHG) and non-muscle invasive low grade (NILG) urothelial bladder cancer (*p-value for RASSF1A, APC and MGMT was <0.001 each-*Mann–Whitney-U Test).
