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Frequency of hypermethylation of tumor suppressor gene loci in urothelial bladder cancer samples
| Tumor suppressor gene | Low grade urothelial carcinoma of urinary bladder (TCC) n = 43 | High grade urothelial carcinoma of urinary bladder (TCC) n = 33 |
|---|---|---|
| RASSF1A | 49% (21/43) | 82% (27/33) |
| APC | 51% (22/43) | 97% (32/33) |
| MGMT | 93% (41/43) | 94% (31/33) |
| CDKN2A | 19% (8/43) | 24% (8/33) |
| CDKN2B | 37% (16/43) | 57% (19/33) |
