Table 1A. Baseline Clinical Characteristics of VAD Patients by AKI Status.
| No AKI (N=113) |
AKI (N=44) |
P value | |
|---|---|---|---|
|
| |||
| Operative Age (years) | 58.3±12.7 | 56.4±12.7 | 0.4 |
|
| |||
| Weight (kg) | 89.2±23.3 | 84.3±25.3 | 0.25 |
|
| |||
| Race N (%) | |||
| Caucasian | 68(60.2) | 23(52.3) | 0.39 |
| African American | 36(31.9) | 18(40.9) | |
| Asian | 4(3.5) | 0 (0) | |
| Unknown | 5(4.4) | 3(6.8) | |
|
| |||
| Males: N (%) | 89(78.8) | 34(77.3) | 0.84 |
|
| |||
| Body mass index (kg/m2) | 28.9±6.3 | 28.4±7.3 | 0.62 |
|
| |||
| Baseline Serum Creatinine (mg/dl) | 1.67± 1.01 | 1.58±0.71 | 0.57 |
|
| |||
| eGFR MDRD (ml/min) | 49.3±26.7 | 50.4±22.1 | 0.82 |
|
| |||
| Pre-operative Hematocrit | 34.2±6.2 | 36.5±5.3 | 0.05 |
|
| |||
| HbA1c | 6.9±1.2 | 6.9±1.2 | 0.84 |
|
| |||
| Diabetes N(%) | 35(31.0) | 23(52.3) | 0.01 |
|
| |||
| Peripheral Vascular Disease N(%) | 7(6.2) | 3(6.8) | 0.85 |
|
| |||
| Hypertension N(%) | 48(42.5) | 23(52.2) | 0.27 |
|
| |||
| Cerebro-Vascular Disease N(%) | 9(8.0) | 9(20.5) | 0.03 |
|
| |||
| Hyperlipidemia N(%) | 61(54) | 21(47.7) | 0.48 |
|
| |||
| CHF N(%) | 101(89.4) | 43(97.7) | 0.09 |
|
| |||
| Ejection Fraction | 17.7 ± 7.6 | 16.5 ±7.9 | 0.57 |
|
| |||
| Cardiogenic Shock N(%) | 34(30.1) | 16 (36.36) | 0.68 |
|
| |||
| VAD Device (N%) | |||
| HeartMate II | 88(77.9) | 35(79.6) | |
| Heartware | 19(16.8) | 5(11.4) | |
| BiVAD | 3(2.7) | 1(2.2) | 0.48 |
| PVAD/RVAD | 0(0) | 1(2.2) | |
| HeartMate XVE | 3(2.6) | 2(4.6) | |
|
| |||
| Goal of Implant N (%) | |||
| Bridge to Transplant | 54(47.8) | 21(48.8) | 0.90 |
| Destination Therapy | 59(52.2) | 22(51.2) | |
|
| |||
| NYHA classification N(=133) (%) | |||
| Class I | 1(1.1) | 1(2.6) | 0.58 |
| Class II | 1(1.1) | 1(2.6) | |
| Class III | 9(9.4) | 4(10.5) | |
| Class IV | 84(88.4) | 32(84.2) | |
|
| |||
| INTERMACS Score (N=147) | |||
| 1 | 18 (17 %) | 11 (26.82 %) | |
| 2 | 46(43.39 %) | 14 (34.14 %) | 0.63 |
| 3 | 25 (23.58 %) | 10 (24.39 %) | |
| 4 | 15(14.15%) | 6(14.63 %) | |
| ≥5 | 2(1.88 %) | 0 | |
|
| |||
| Preoperative Hemodynamics (N=111) | |||
| RAP (mm-hg) | 13.7±6.6 | 14.5±7.5 | 0.60 |
| RVSP (mm-hg) | 53.3±14.8 | 51± 12.7 | 0.45 |
| PASP (mm-hg) | 54.3±15.1 | 51.6±13.9 | 0.40 |
| PADP (mm-hg) | 26.9±8.5 | 26.5±7.2 | 0.84 |
| PCWP | 25.9±8.7 | 23.6±10.2 | 0.25 |
| Cardiac Output (L/min) | 3.78±1.7 | 3.60±1.4 | 0.62 |
| Cardiac Index | 1.84±0.6 | 1.82±0.7 | 0.87 |
eGFR – Estimated Glomerular Filtration Rate
RAP- Right Atrial Pressures
RVSP- Right Ventricle Systolic pressure
PASP – Pulmonary artery Systolic Pressure.
PADP- Pulmonary artery diastolic pressure
PCWP – Pulmonary capillary wedge pressure.
PVAD/RVAD- Paracorporeal ventricular /Right ventricular assist device.
Data presented as either mean ± SD or median (inter-quartile range) as appropriate