Table 3. Studies of immunogenicity of inactivated hepatitis A vaccines produced in China (TZ84).

Study	Subjects (No.)	Duration of follow up after first dose (months)	Mean GMT	Seroconversion, %	Dosage	Number of doses received (months)	Age group (year)
Ren A, 200150	16	1	139	94	1000 U	1	18–21
	16	3	138	100	1000 U	1
	16	7	1067	100	1000 U	2 (0,6)
Ren Y, 200251	63	1	182	86	500 U	1	1–4
		3	243	89	500 U	1
		6	280	84	500 U	1
	37	7	4683	100	500 U	2 (0,6)
	26	7	2718	100	500 U	2 (0,6)
Liu C, 200252	32	1	174	94	1000 U	1	5–15
	75	5	5160	100	1000 U	2 (0,3)
	55	7	7540	100	1000 U	2 (0,6)
	32	1	146	91	500 U	1
	57	5	3269	100	500 U	2 (0,3)
	50	5	4535	100	500 U	2 (0,3)
Ren Y, 200253	32	1	342	63	125 U	1	4–10
	33	1	382	94	250 U	1
	33	1	391	100	250 U	1
	32	6	531	100	125 U	2 (0,1)
	32	7	3170	100	125 U	3 (0,1,6)
	33	7	5963	100	250 U	2 (0,6)
Ren A, 200223	32	1	175	88	1000 U	1	18–20
	31	6	264	97	1000 U	1
	32	7	2747	100	1000 U	2 (0,6)
	40	1	159	70	500 U	1
	26	6	259	65	500 U	1
	40	7	1657	100	500 U	2 (0,6)
Ren Y, 200354	39	1	371	97	500 U	1	5–15
	49	1	320	100	500 U	1
	70	1	321	99	500 U	1
	33	1	355	97	250 U	1
	38	1	195	95	250 U	1
	67	1	251	96	250 U	1
	31	5	6611	100	250 U	2 (0,3)
	36	5	7154	100	250 U	2 (0,3)
	39	3	2800	100	250 U	2 (0,1)
	34	5	3265	100	250 U	2 (0,3)
	33	7	5963	100	250 U	2 (0,6)
	33	3	1973	100	250 U	2 (0,1)
Ren Y, 200354	34	3	417	100	250 U	1	5–10
	33	6	391	100	250 U	1
	36	12	361	100	250 U	1
	33	3	1973	100	250 U	2 (0,1)
	34	5	3265	100	250 U	2 (0,3)
	33	7	5963	100	250 U	2 (0,6)
	36	7	14 893	100	250 U	2 (0,12)
Ren Y, 200354	36	13	195	94	250 U	1	4–10
	36	12	360	100	250 U	1
	49	1	370	100	500 U	1
	49	12	456	100	500 U	1
	36	13	14 893	100	250 U	2 (0,12)
	49	13	21 696	100	500 U	2 (0,12)
Li Y, 200355	97	1	758.6	95	720 EIU	1	Children (average age, 9.7 years)
	105	6	2951	99	720 EIU	1
	99	7	10 471	100	720 EIU	2 (0,6)
	120	1	3631	97	1440 EIU	1	Adults (average age, 17.2 years)
	119	6	2455	100	1440 EIU	1
Ren Y, 200354	52	12	869	100	500 U	2 (0,3)	5–10
	58	24	782	100	500 U	2 (0,3)
	58	36	379	100	500 U	2 (0,3)
	55	12	981	100	500 U	2 (0,6)
	55	24	667	100	500 U	2 (0,6)
	55	36	462	100	500 U	2 (0,6)
Yao J, 200456	73	2	260	95	250 U	1	2–3
Jia X, 200457	91	1	14 407	100	250 U	1	2–15
Jiang W, 20089	122	1	28	75	250 U	1	1–3
	125	6	118	97	250 U	1
	121	7	3106	100	250 U	2 (0,6)
	167	1	29	75	250 U	1	4–8
	168	6	103	97	250 U	1
	166	7	3686	100	250 U	2 (0,6)