Table 3.

Robust regression estimates of gene–environment interactions of log telomere length

Measure	Model 1	Model 2	Model 3	Model 4
Harsh environment	−0.02	−0.03	−0.10	−0.18
Serotonin
A. Count of homozygous sensitizing allele genotypes	0.01
B. Count of sensitizing alleles		0.03
Dopamine
A. Count of homozygous sensitizing allele genotypes			0.06
B. Count of sensitizing alleles				−0.02
Interactions
Serotonin A × Harsh environment	−0.22*
Serotonin B × Harsh environment		−0.21*
Dopamine A × Harsh environment			−0.18†
Dopamine B × Harsh environment				−0.07

Serotonin A and dopamine A refer to a genetic sensitivity score (0–4) equal to the number of homozygous genotypes composed of sensitizing alleles of serotonergic or dopaminergic pathway genes, respectively. Serotonin B and dopamine B refer to a genetic sensitivity score (0–8) equal to the number of sensitizing alleles of serotonergic or dopaminergic pathway genes, respectively. All models control for age of mother and age 9 BMI. All gene scores are mean centered. ^†P < 0.10, *P < 0.05, one-tailed.