Fig. 5.

Altered annexin A6 intracellular localization in myofibers with disrupted membranes. Sgcg¹²⁹ and Sgcg^D2 mice were injected with Evans blue dye (Dye, red) to mark damaged muscle fibers. Shown are representative images of Sgcg¹²⁹ and Sgcg^D2 muscle immunostained with an antibody to the amino terminus of annexin A6 (green). Annexin A6 strongly localized in discrete patches on the periphery of dye-positive Sgcg¹²⁹ fibers (top row, white arrow). Annexin A6 was only weakly present on the periphery of dye-positive Sgcg^D2 fibers (dotted arrow).