Table 2.
Diastolic and systolic function in normal pregnancy and preeclampsia
|
Parameters |
Normal pregnancy |
Preeclampsia |
P-values |
|---|---|---|---|
|
(n = 40) |
(n = 23) |
||
| Left heart size | |||
| LA size, mm |
32.1 ± 3.1 |
35.1 ± 4.7 |
0.0034 |
| LVEDD, mm |
44.2 ± 3.1 |
46.0 ± 5.3 |
0.0913 |
|
Diastolic function |
|
|
|
| E wave, cm/s |
83.9 ± 15.1 |
93.0 ± 31.6 |
0.1361 |
| A wave, cm/s |
61.6 ± 14.2 |
75.7 ± 17.2 |
0.0011 |
| E/A ratio |
1.41 ± 0.31 |
1.24 ± 0.36 |
0.0658 |
| Septal e wave, cm/s |
13.8 ± 2.2 |
10.3 ± 3.4 |
<0.00001 |
| Septal a wave, cm/s |
12.0 ± 3.0 |
11.9 ± 3.2 |
0.8682 |
| Septal e/a ratio |
1.20 ± 0.28 |
0.90 ± 0.38 |
0.0007 |
| Lateral e wave, cm/s |
17.8 ± 2.9 |
14.3 ± 3.8 |
0.0001 |
| Lateral a wave, cm/s |
12.1 ± 3.3 |
12.6 ± 2.0 |
0.4946 |
| Lateral e/a ratio |
1.58 ± 0.49 |
1.15 ± 0.38 |
0.0010 |
| Septal E/e ratio |
6.06 ± 1.92 |
9.95 ± 4.39 |
<0.00001 |
| Lateral E/e ratio |
4.75 ± 1.56 |
6.77 ± 2.28 |
<0.00001 |
|
Systolic function |
|
|
|
| Ejection fraction |
0.66 ± 0.05 |
0.68 ± 0.10 |
0.2561 |
| Fractional shortening (%) | 36.6 ± 5.0 | 38.4 ± 8.2 | 0.2848 |
Notes: LA, left atrium; LVEDD, left ventricular end-diastolic dimension; E and A, transmitral flow velocity during early diastole and atrial contraction; e and a, mitral annular tissue velocities during early and late diastole.