Table 3.
Hemodynamic changes and cardiac remodeling in normal pregnancy and preeclampsia
| Parameters |
Normal pregnancy |
Preeclampsia |
P-values |
|---|---|---|---|
| (n = 40) | (n = 23) | ||
|
Hemodynamic indices |
|
|
|
| HR, bpm |
93 ± 15 |
89 ± 14 |
0.3100 |
| CI, L/min/m2 |
2.99 ± 0.56 |
3.07 ± 0.72 |
0.5760 |
| TPRI, (dynes × s-1 × cm-5)/m2 |
723.0 ± 123.3 |
894.1 ± 303.6 |
0.0023 |
|
LV remodeling indices |
|
|
|
| RWT |
0.44 ± 0.06 |
0.46 ± 0.09 |
0.3475 |
| LVMI, g/m2 |
96.3 ± 17.8 |
110.9 ± 29.0 |
0.0005 |
|
LV geometric pattern |
|
|
|
| Normal |
16 (40) |
1 (4) |
<0.0001 |
| Concentric remodeling |
20 (50) |
2 (8) |
<0.0001 |
| Eccentric hypertrophy |
0 (0) |
6 (26) |
<0.0001 |
| Concentric hypertrophy | 4 (10) | 14 (62) | <0.0001 |
Notes: Values are given as mean ± SD or no. of subjects (percentage). HR, heart rate; CI, cardiac index; TPRI, total peripheral resistance index; RWT, relative wall thickness; LVMI, left ventricular mass index; LV, left ventricle.