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HbA1c levels in control nondiabetic ZDF (+/+) and diabetic ZDF (fa/fa) rats nontreated and treated with 10 mg/kg/day sitagliptin for 6 weeks, at 26 weeks of age. Data are expressed as mean ± SEM (n ≥ 6 per group); ***P < 0.001 significantly different from control; ## P < 0.01 significantly different from diabetic.
