Table 1.
Body weight and glycaemia in the control and diabetic ZDF rats, nontreated and treated with sitagliptin for 6 weeks.
| Time | Initial time (20 wks) | Final time (26 wks) | |||
|---|---|---|---|---|---|
| Rat group | Control | Diabetic | Control | Diabetic | |
| Parameters | (n = 8) | (n = 16) | Vehicle (n = 8) | Vehicle (n = 8) | Sita (n = 8) |
| BW (g) | 407.8 ± 7.3 | 394.6 ± 6.5 | 438.2 ± 4 | 370.4 ± 11.8** | 389.5 ± 15.7 |
| Glycaemia (mg/dL) | 92.3 ± 2.5 | 304.6 ± 9.1*** | 88.8 ± 2.9 | 425.4 ± 10.3*** | 329.8 ± 24.4### |
Values are means ± SEM of n rats. **P < 0.01 and ***P < 0.001 significantly different from age-matched control; ### P < 0.001 significantly different from age-matched diabetic.