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. 2014 Apr 22;8:21. doi: 10.3389/fnana.2014.00021

Table 1.

Somatosensory cell type markers.

Marker Sensory cell type
Parvalbumin Proprioceptors and Aβ fibers
CGRP Peptidergic C fibers, sub-population of Aδ fibers
Substance P Peptidergic C fibers
NF200 Myelinated Aδ fibers, Aβ fibers, and proprioceptors
IB4 Non-peptidergic C fibers
Trpv1 Small diameter C fibers (heat and pain)
Trpm8 Small diameter C fibers (cold and pain)
MrgprD Small diameter C fibers (noxious mechanical, pain)
MrgprA3 Small diameter C fibers (itch)
MrgprB4 Small diameter C fibers (innocuous mechanical)
VGlut3 Non-peptidergic C fibers (innocuous mechanical, cooling)
TH Non-peptidergic C fibers (innocuous mechanical, cooling)
TrkB Aδ fibers (innocuous mechanical, cooling)
Npy2r Aβ fibers (innocuous mechanical)
Chondrolectin Aβ fibers (innocuous mechanical)
DOR Sub-populations of non-peptidergic C fibers and myelinated NF200-positive fibers

Abbreviations: CGRP, calcitonin gene-related peptide; NF200, neurofilament heavy chain 200; IB4, isolectin B4; Trpv1, transient receptor potential cation channel subfamily V member 1; Trpm8, transient receptor potential cation channel subfamily M member 8; MrgprD, Mas-related G-protein-coupled receptor D; MrgprA3, Mas-related G-protein-coupled receptor A3; MrgprB4, Mas-related G-protein-coupled receptor B4; VGluT3, vesicular glutamate transporter type 3; TH, tyrosine hydroxylase; TrkB, tyrosine receptor kinase B; Npy2r, neuropeptide Y receptor type 2; DOR, delta opioid receptor.