Table 3.
Co-variate | Outcome: HIV positivity OR (95% CI; p-value) |
---|---|
Univariate analyses | |
TLR3 rs3775291 | |
Non-T allelea | 1.0 |
T allele | 0.29 (0.09–0.90, 0.03) |
Age | |
Yearsb | 1.03 (0.94–1.13, 0.51) |
Gender | |
Malea | 1.0 |
Female | 0.88 (0.30–2.57; 0.81) |
HCV serostatus | |
HCV−a | 1.0 |
HCV+ | 14.08 (2.89–68.53; <0.01) |
HBV serostatus | |
HBV−a | 1.0 |
HBV+ | 6.09 (2.02–18.36; <0.01) |
Duration of intravenous drug use Yearsb | 1.12 (1.01–1.24; 0.02) |
Multivariate analyses | |
TLR3 rs3775291 | |
Non-T allelea | 1.0 |
T allele | 0.25 (0.07–0.87; 0.03) |
HCV serostatus | |
HCV−a | 1.0 |
HCV+ | 15.35 (2.46–95.69; <0.01) |
HBV serostatus | |
HBV−a | 1.0 |
HBV+ | 1.25 (0.50–3.11; 0.63) |
Duration of intravenous drug use Yearsb | 1.11 (1.00–1.23; 0.06) |
Note: OR, odds ratio; CI, confidence interval.
Reference group.
Years were categorized as a continuous variable in full-years, and data reflects an increase in OR with each additional year of age or intravenous drug use.