Table 4. Change in methylation of NBL2 associated with 10% increase in inhaled elemental components a.
Office Workers (obs=120) | Truck Drivers (obs=120) | |||||||
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β | 95%CI | p-value | FDR | β | 95%CI | p-value | FDR | |
Inhaled elemental componentsb | ||||||||
Al | -0.077 | (-0.219 ; 0.066) | 0.291 | 0.810 | 0.096 | (-0.007 ; 0.199) | 0.067 | 0.180 |
Ca | 0.023 | (-0.092 ; 0.138) | 0.692 | 0.810 | 0.065 | (0.014 ; 0.115) | 0.012 | 0.047 |
Fe | 0.013 | (-0.095 ; 0.121) | 0.810 | 0.810 | 0.054 | (-0.027 ; 0.135) | 0.189 | 0.377 |
K | -0.056 | (-0.181 ; 0.068) | 0.375 | 0.810 | 0.035 | (-0.046 ; 0.117) | 0.396 | 0.528 |
S | 0.020 | (-0.046 ; 0.085) | 0.554 | 0.810 | -0.003 | (-0.092 ; 0.087) | 0.954 | 0.954 |
Si | 0.010 | (-0.063 ; 0.082) | 0.795 | 0.810 | 0.121 | (0.030 ; 0.212) | 0.009 | 0.047 |
Ti | 0.060 | (-0.030 ; 0.151) | 0.192 | 0.810 | 0.044 | (-0.045 ; 0.133) | 0.331 | 0.528 |
Zn | -0.024 | (-0.092 ; 0.043) | 0.479 | 0.810 | -0.004 | (-0.059 ; 0.051) | 0.890 | 0.954 |
Based on 240 total observations (120 study days for office workers and 120 study days for truck drivers). P-values were obtained from GEE models, which were adjusted for occupation, PM2.5, measure day, age, sex, BMI, number of cigarettes smoked during examination time and usage of central heating.
Measured during the work hours of examination days using light-weight personal monitors.