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. Author manuscript; available in PMC: 2014 Apr 28.
Published in final edited form as: In Vivo. 2013 Sep-Oct;27(5):599–603.

Figure 4.

Figure 4

Photomicrographs of the lung metastases in a mouse 12 weeks after undergoing surgical implantation of solid osteosarcoma tumor fragments. A: Variably-sized nodules composed of neoplastic osteoblasts surrounding a central region of coagulation necrosis (N) with occasional dystrophic mineralization (arrow), x0.5 magnification. B,C: Higher magnification of the coagulation necrosis (N); some neoplastic cells produce eosinophilic, osteoid-like matrix (O), x20 magnification. Hematoxylin and eosin staining.