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Cell cycle arrest by CuE in CRC cells via inhibition of CDC2. The CRC Cells (CP3 and CP4) were treated with CuE followed by (a) western blotting analysis (upper) and Co-IP (lower); (b) quantification of intensities by Li-COR near infrared imaging system; (c) delay in mitosis in CuE-treated CRC cells via the inhibition of Cdc2-cyclin B1 complex dissociation. Significant differences were set at a level of *P<0.05 versus the 0 μM CuE control group
