Table 2. Profile of Kinase Inhibition by 25 μM Solution of 8^a.

	% of control	SD, %
25 μM Solution of 8
control	100	0
ERK1	55	5
RSK2	27	1
NUAK1	49	6
PIM3	46	4
BTK	42	1

^a109 different protein kinases were tested for their inhibition by 8. The five kinases that were inhibited most strongly are reported in this table. All other kinases were affected less. Most of them are not affected at all. Screening was performed by the National Centre for Protein Kinase Profiling, Division of Signal Transduction Therapy, University of Dundee. The data are portrayed as mean % activity and standard deviation of assay duplicates.