Table 4. In vitro antiviral activity of SKHSSLDCVLRP, AGDDQGLDKCVPNSKEK, and NGESSADWAKN peptides towards influenza virus infection.
| Viral strain | Subtype | CC50* | EC50° | SÎ | |
| SKHSSLDCVLRP | A/Roma-ISS/2/08 | H1N1 | >25 μM | 4±0.37 pM | >6.25×106 |
| A/Parma/24/09 | H1N1 | >25 μM | 3.1±0.12 pM | >8×106 | |
| A/Parma/05/06 | H3N2 | >25 μM | 5.8±0.7 pM | >4.3×106 | |
| AGDDQGLDKCVPNSKEK | A/Roma-ISS/2/08 | H1N1 | >25 μM | 3.7±0.35 pM | >6.75×106 |
| A/Parma/24/09 | H1N1 | >25 μM | 3.4±0.14 pM | >7.35×106 | |
| A/Parma/05/06 | H3N2 | >25 μM | 7.3±0.65 pM | >3.42×106 | |
| NGESSADWAKN | A/Roma-ISS/2/08 | H1N1 | >25 μM | 225±5.8 fM | >1.11×108 |
| A/Parma/24/09 | H1N1 | >25 μM | 50±1.37 fM | >5×108 | |
| A/arma/05/06 | H3N2 | >25 μM | 22.5±1.16 pM | >1.11×106 |
Note: *CC50 the reciprocal substance dilution at which 50% of cells were protected from substance toxicity; °EC50 the reciprocal substance dilution at which 50% of cells were protected from the virus induced killing; ˆSI (selectivity index) the ratio between CC50 and EC50.
The mean values of three independent experiments with standard errors are shown.