. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Clin Pharmacol Ther. 2013 Jun 11;94(4):525–532. doi: 10.1038/clpt.2013.119
Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms