Fig. 3. β-oxidation and lipid partitioning in the liver of wild-type and Plin2−/− mice after PH.
(A) Quantitative RT-PCR analysis of mRNA expression of genes related to lipid metabolism at 24 h (24) and 36 h (36) after PH (n = 4). (B) Thin-layer chromatography analysis of lipids in cytosolic and microsomal compartments isolated from wild-type and Plin2−/− livers 36 h after PH. (C) Quantification of cytosolic and microsomal triglyceride and fatty acids content in livers of wild-type, and Plin2−/− mice 36 h after PH (n = 5). (D) Serum β-HBA from wild-type and Plin2−/− mice (n = 5) at basal and different time points after PH. In all panels, data are expressed as means ± S.D. *p <0.05 and **p <0.01 vs. wild-type group. WT, wild-type; KO, Plin2−/−; TG, triglyceride; FA, fatty acids.