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. 2014 Mar 5;592(Pt 8):1839–1856. doi: 10.1113/jphysiol.2013.268706

Figure 3. Effects of hypoxia and sham ACSF injections on ventilation in CON and CSH rats.

Figure 3

A, effect of hypoxia and ACSF microinjections on VI. B, effect of hypoxia and ACSF on fR. C, effect of hypoxia and ACSF on VT. D–F, effect of ACSF microinjections on hypoxic ventilatory response and hypercapnic ventilatory response of VI (D), fR (E) and VT (F). Data are the time response following bilateral microinjections of NMDA in the presence (continuous lines) or absence (dotted lines) of ACSF. Data are means ± s.e.m. from n = 7 animals per group. *Significant differences between CON and CSH values (P < 0.05). ACSF, artificial cerebral spinal fluid; CON, controls; CSH, chronic sustained hypoxia; fR, breathing frequency; VI, total minute ventilation; VT, tidal volume.