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. 2014 Mar 5;592(Pt 8):1839–1856. doi: 10.1113/jphysiol.2013.268706

Figure 10. Arterial blood gases are not changed by NMDA or AMPA receptor antagonism.

Figure 10

A, average changes in Inline graphic and Inline graphic in response to microinjection of the NMDA receptor antagonist MK801 into the nucleus tractus solitarius of CON and CSH rats breathing acute levels of 10% and 21% O2. B, average changes in Inline graphic and Inline graphic in response to microinjection of the AMPA receptor antagonist NBQX into the nucleus tractus solitarius of CON and CSH rats breathing acute levels of 10% and 21% O2. All blood gases are corrected for body temperature. Numbers refer to the following: (1) CON rats breathing 21% O2; (2) CON rats breathing 10% O2; (3) CSH rats breathing 10% O2; (4) CSH rats breathing 21% O2. Data are means ± s.e.m. from n = 3 rats per group. Significance was assessed as P < 0.05. CON, controls; CSH, chronic sustained hypoxia.