Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Feb;143(2):145–156. doi: 10.1085/jgp.201311103

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Palovcak et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

PMC Copyright notice

Figure 1. — The register of S4 is not ambiguous. (A) Positional posterior probability of the Needleman–Wunsch optimal pairwise alignment of Kv1.2 and human Hv1. (B) Positional posterior probabilities of alignments sampled from the pair HMMs underlying the ppAlign algorithm. Each alignment represents a different possible register for the S4 helix of Hv1 with respect to Kv1.2.