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. Author manuscript; available in PMC: 2014 Apr 28.
Published in final edited form as: JAMA Neurol. 2013 Jan;70(1):78–84. doi: 10.1001/jamaneurol.2013.579

Figure 5.

Figure 5

The triggering receptor expressed on myeloid cells 2 gene (TREM2) structure spans 41126246 to 41130922 base pairs (bp) on chromosome (chr) 6p21.1. A, Schematic of TREM2 (drawn using FancyGene19), the mutation nomenclature given with respect to RefSeq identifier NM_018965.2. Exons are drawn to scale and represented with gray boxes with untranslated regions (UTR) in red. Mutation locations are approximate: mutations identified in this study are represented below and previously described mutations are represented on top. B, The conservation of mutations identified in the present study. GenBank accession numbers: NP_061838.1, Homo sapiens; XP_001174113.1, Pan troglodytes;XP_851231.1, Canis lupus; NP_001073048.1, Bos taurus; NP_112544.1, Mus musculus; XP_217335.3,Rattus norvegicus; and NP_001032921.1, Gallus gallus.