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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: NMR Biomed. 2013 Oct 3;26(12):1609–1629. doi: 10.1002/nbm.3025

Figure 7.

Figure 7

An example of the two two-point Dixon technique, demonstrated in a subject with known non-alcoholic fatty liver disease (24% hepatic fat-signal fraction previously determined by spectroscopy). Two sets of images are acquired in a single scan with water and methylene fat signals (A) in-phase (IP) and (B) out-of-phase (OP). Note that the liver signal intensity (dashed arrow) in the OP image is markedly darker than in the IP image, indicative of possible steatosis. Similar signal variations can be observed in the pancreas (dotted tracing) and to a lesser extent in the muscles. Note that IP and OP signal variations are not observed in the subcutaneous and visceral adipose tissues (fat-dominant). For comparison, note also the vertebral bone marrow (arrow), which contains near equal amounts of water and fat. This leads to a near complete cancellation of water and fat signals in the OP image.