. Author manuscript; available in PMC: 2014 Apr 28.

Published in final edited form as: Neurobiol Dis. 2012 Mar 9;46(3):692–700. doi: 10.1016/j.nbd.2012.03.010

Table 2.

Precision of carbamazepine, carbamazepine-epoxide, quinolinic acid quantification.

Drugs/metabolites	Concentration added (μg/ml)	Intraday			Correlation (r)

		Measured concentration (mean±SD)	CV (%)^a	Accuracy (%)^b
Carbamazepine	1	1.043 ± 0.060	5.752	104.30	0.999
	5	4.979 ± 0.157	3.153	99.58
	10	10.201 ± 0.186	1.823	102.01
	25	25.351 ± 0.312	1.230	101.40
	50	49.761 ± 0.305	0.612	99.52
Carbamazepine-epoxide	1	0.994 ± 0.057	5.734	99.40	0.998
	5	4.973 ± 0.183	3.679	99.46
	10	9.952 ± 0.023	0.231	99.52
	25	24.828 ± 0.192	0.773	99.31
	50	49.939 ± 0.182	0.364	99.87
QA method-1	0.84	0.838 ± 0.033	3.93	99.76	0.998
	1.68	1.689 ± 0.016	0.945	100.53
	4.20	4.198 ± 0.213	5.073	99.95
	8.40	8.422 ± 0.089	1.056	100.26
	16.80	16.762 ± 0.141	0.841	99.77
QA method-2	0.84	0.849 ± 0.033	3.866	101.07	0.999
	1.68	1.682 ± 0.018	1.070	100.11
	4.20	4.221 ± 0.123	2.914	100.50
	8.40	8.413 ± 0.312	3.708	100.15
	16.80	16.81 ± 0.213	1.267	100.05

Mean values represent five different samples of each concentration.

Accuracy = 100 (observed concentration/theoretical concentration).

CV % or relative standard deviation % = 100 (standard deviation/mean).