Figure 7.
L. major infection does not inhibit IFN-γ-induced IRF-1 or IRF-8 nuclear translocation. WT and CD11b KO MP were infected for the indicated times with or without subsequent IFN-γ stimulation for 2 hr. Nuclear fractions were analyzed for presence of IRF-1 or IRF-8 by western blot analysis. Lamin A/C was assessed as a loading control. One representative of three independent experiments is presented.