Table 2. Relative biological parameters of different cell groups after calculated by multi-target single-hit model.
| Cell groups | Eca-109 |
TE-1 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| D0 | Dq | D37 | N | SF10 | D0 | Dq | D37 | N | SF10 | |
| Blank | 4.0160 | 3.6314 | 7.6475 | 2.4700 | 0.1925 | 3.8023 | 3.6185 | 7.4208 | 2.5901 | 0.1851 |
| Prx1 siNeg | 4.0241 | 3.7038 | 7.7279 | 2.5103 | 0.1961 | 3.8609 | 3.6938 | 7.5548 | 2.6031 | 0.1903 |
| Prx1 siRNA | 3.7722 | 2.6614 | 6.4336 | 2.0250 | 0.1448 | 3.5474 | 2.7842 | 6.2956 | 2.1710 | 0.1190 |
| Prx5 shNeg | 4.0568 | 3.6203 | 7.6771 | 2.4410 | 0.1899 | 3.8125 | 3.6179 | 7.4373 | 2.5793 | 0.1877 |
| Prx5 shRNA | 3.4188 | 2.5202 | 5.9390 | 2.0901 | 0.1089 | 3.2594 | 2.5101 | 5.7696 | 2.1601 | 0.0978 |
| Combined Neg | 3.9761 | 3.7102 | 7.6863 | 2.5424 | 0.1881 | 3.7864 | 3.6331 | 7.4195 | 2.6104 | 0.1839 |
| Combined | 3.1456 | 1.8314 | 4.9770 | 1.7902 | 0.0733 | 3.0395 | 1.8552 | 4.8947 | 1.8411 | 0.0675 |
D0: mean lethal dose; Dq: quasithreshold dose; D37: dose for 37% survival; N: the extrapolation number; SF10: the survival fraction (SF) after irradiation at a dose of 10 Gy.