Figure 3.
The MIF inhibitor, ISO-1 reduces endometriotic implant mass. Endometriosis was induced and mice were subsequently treated as described in Materials and Methods. Average endometriotic implant size (mm3) was calculated between treatment groups. Data are displayed as the mean ± SD and are representative of 10 mice per treatment group (N=10). Data was analyzed by unpaired t-tests. Significance was set at p < 0.05 for all comparisons. Asterisks (*) indicates statistical significantly different means. Broken line indicates size of implants at start of experiment (1 mm3).