Effects of Sj7170 on cell proliferation and colony formation in vitro.
A, dose-dependent effect of Sj7170 on the proliferation of U87 cells. Results are means ± S.D. B, time-dependent effect of Sj7170 on the proliferation of U87 cells. Results are means ± S.D. C, effect of Sj7170 on tumor cell growth by monolayer colony formation assay. Left panel, representative plates for the colony formation assay. Right panel, statistical results. D, cell cycle analysis of U87 treated by Sj7170 using flow cytometry. U87 cells were treated with different concentrations of Sj7170 for 48 h. c, control.