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1,25(OH)2D3 inhibits the expression and secretion of proinflammatory cytokines in macrophages. A and B, effect of 1,25(OH)2D3 on mRNA expression of TNF-α and IL-6 in RAW264.7 cells in presence and absence of LPS stimulation. *, p < 0.05; n = 6. C and D, effect of 1,25(OH)2D3 on secretion of TNF-α and IL-6 in RAW264.7 cells in absence and presence of LPS stimulation. *, p < 0.05; n = 6. Ctrl, control.
