TABLE 1.
Amino acid sequence of class II α and β chain transmembrane domains1
1. Predicted transmembrane domains are underlined in I-A sequences.
2. Gray boxes — GXXXG motifs in I-A.
3. I-A consensus sequence based on seven I-A alleles (k, b, d, f, q, s, u).
4. DQA1*01:01:01 protein sequence from EMBL/EBI IMGT/HLA database.
5. All 7 DRA protein sequences from EMBL/EBI IMGT/HLA database.
6. All 10 DPA protein sequences from EMBL/EBI IMGT/HLA database.
7. NCBI Reference Sequence: NP_034511.2.
8. Consensus of most DQB protein sequences from EMBL/EBI IMGT/HLA database.
9. Consensus of most DRB protein sequences from EMBL/EBI IMGT/HLA database.
10. Consensus of most DPB protein sequences from EMBL/EBI IMGT/HLA database.
11. NCBI Reference Sequence: NP_034512.2.