FIGURE 4.

Monovalent ion (Li⁺, Na⁺, K⁺, and Cs⁺) permeability through snail LCav3 T-type channels is especially dramatic with exon 12a compared with exon 12b extracellular turrets or human Cav3. 1 channels. Inward calcium currents in 4 mm [Ca²⁺]_ex and outward monovalent T-type channel currents were generated with intracellular solutions containing 100 mm of Li⁺, Na⁺, K⁺, or Cs⁺ and elicited from a −110-mV holding potential in voltage steps from −90 to +80 mV in 5-mV increments. A, representative currents; B, their current-voltage relationships. n values are shown in parentheses. A or B, inset, close-up of currents crossing the reversal potential, with reversal potentials labeled in B. Statistics for Fig. 4 are shown in Table 5.