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. 2014 Mar 24;2(3):e00264. doi: 10.1002/phy2.264

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© 2014 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Plasma and Kidney angiotensin II and angiotensin (1–7) levels. (A) No difference between plasma angiotensin II in ACE2 KO and WT mice. Whole kidney samples of ACE2 KO showing levels of Ang II also not different from those of the WT mice. (B) No difference between plasma angiotensin (1–7) in ACE2KO and WT mice. Whole kidney samples in ACE2KO showing levels of Ang(1–7) significantly higher than in the WT mice (*P < 0.05; n = 10 WT, n = 6 ACE2KO).