Figure 3.

Effects of LPC and Aβ_1–42 on calcium levels in SH-SY5Y cells. Calcium levels were measured as described under Materials and Methods. (A) LPC (10 μmol/L) augmented the effect of Aβ_1–42 (10 μmol/L) on calcium levels. (B) After depletion of the Ca²⁺ store by the addition of TG (1 μmol/L) for 1 h, Aβ_1–42 could not change the cytosolic calcium concentration. Data were expressed as means±SEM from three independent experiments.