Figure 1.

Mean plasma concentration-time profiles of cyclosporine in CYP3A4^*1/^*1 (A), CYP3A4^*1/^*18B (B), and CYP3A4^*18B/^*18B (C) subjects who were administered a single oral dose of cyclosporine (4 mg/kg) after treatment with placebo or bifendate. Data are expressed as mean±SEM.