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. 2010 Aug 23;31(9):1111–1117. doi: 10.1038/aps.2010.146

Table 1. CR effect on signal molecule.

Signal molecule	CR effect on signal molecule	Ref No
AP-1	↓	^{81, 95}
FOXO	↓	^{89, 97}
GSK-3β	↓	^{93, 98}
HIF-1	↓	^{95, 99}
HSF-1	↑	⁹⁴
HSP-70	↑	^{94, 100}
mTOR	↓	^{90, 101}
NF-κB	↓	^{81, 82, 95, 97}
PGC-1α	↑	^{91, 92}
PPAR α	↑	^{91, 102}
SIRT1	↑↓	^{92, 93, 103}

↑=increase in signal transduction; ↓=decrease in signal transduction.