Table 3. Genotype distribution in patients with ischemic and hemorrhagic stroke and control subjects.

SNP	Genotype	Controls	Ischemic stroke (n=564)			Hemorrhagic stroke (n=220)
		(n=564)		Crude	Adjusted		Crude	Adjusted
		n	n	P value	P value	n	P value	P value
rs2794521	Additive
	AA	398	386	0.110	0.009b	143	0.247	0.164
	AG	155	155			70
	GG	11	23			7
	Recessive
	AA+AG	553	541	0.037b	0.003b	213	0.301	0.142
	GG	11	23			7
	Dominant
	AA	398	386	0.438	0.202	143	0.130	0.135
	GG+AG	166	178			77
rs3091244	Additive
	CC	323	340	0.125	0.262	137	0.358	0.357
	CA	157	134			57
	CT	53	60			12
	AA	19	15			11
	TT	5	3			1
	AT	7	12			2
rs1205	Additive
	TT	173	172	0.440	0.194	68	0.686	0.109
	TC	297	282			110
	CC	94	110			42
	Recessive
	TT+TC	470	454	0.216	0.085	178	0.421	0.056
	CC	94	110			42
	Dominant
	TT	173	172	1.000	0.999	68	0.949	0.793
	TC+CC	391	392			152

Crude P values were determined by a 95% two-sided χ² test. Adjusted P value was calculated by multiple logistic regression analysis with adjustment for age, sex, BMI, history of hypertension, hyperlipidemia, diabetes mellitus and smoking.

^bP<0.05 vs controls.