Figure 4.

Effect of ginsenoside Rg1 on migratory activity of endothelial progenitor cells (EPCs) in dose- and time-course experiments using a modified Boyden chamber assay. In EPCs treated with ginsenoside Rg1, there was a dose-dependent increase in EPC migratory activity (A). In cells treated with 5.0 μmol/L ginsenoside Rg1, there was a time-dependent increase in EPC migratory activity (B). Enhanced EPC migratory activity became apparent after 6 h and reached its maximum at 24 h. ▪ vehicle control, ♦ 5.0 μmol/L ginsenoside Rg1. Data are presented as the mean±SD. n=5. ^bP<0.05, ^cP<0.01 compared with vehicle control.