Figure 3.

Time- and dose-dependence of the LC-induced up-regulation of TAU uptake in VSMC monolayers. (A) Cells were precultured for 48 h in medium containing various concentrations of LC as indicated. Uptake experiments were then performed as described in Materials and methods. Each value is the mean±SD. n=4. ^bP<0.05 vs control. (B) VSMCs were precultured in medium containing 10 mmol/L LC for various time (0−60 h) as indicated, and uptake experiments were performed as described in Materials and methods. Each value is the mean±SD. n=4. ^bP<0.05 vs control.