Table 1. Histopathological lung injury score, interalveolar septal thickness and the number of neutrophils in alveolar spaces in mice at 24 h during LPS-induced lung injury.
Measure | Untreated control | LPS and PBS | LPS and CXCR4 antagonist |
---|---|---|---|
Lung injury score | 1.1±0.1 | 3.3±0.1 | 2.5±0.2* |
Septal thickness (µm) | 1.6±0.1 | 2.9±0.1 | 2.5±0.1* |
No. of neutrophils in 100 alveoli | 1.2±0.3 | 68.3±4.6 | 48.5±2.9* |
Abbreviations: LPS, lipopolysaccharide; PBS, phosphate-buffered saline.
Data are represented as mean±s.e.m. n=6 per group.
*P<0.01 versus LPS and PBS group.