Table 1. Cell culture conditions.
Cells | Number/well | V/well (mL) | Plate | Stimulation | Read-out | Incubation time |
---|---|---|---|---|---|---|
SPC | 5.0×106 | 1 | 24-well | ConA 2.5 µg/mL | MTT assay, Griess reaction | 24 h |
DLNC | 2.5×106 | 1 | 24-well | MBP 10 ng/mL | AP assay, ELISA, RT-PCR | 24 h |
PC | 2.0×106 | 1 | 24-well | LPS 10 ng/mL | CV assay, Griess reaction | 24 h |
PC | 2.0×106 | 1 | 24-well | LPS 10 ng/mL | Cytofluorimetry | 30 min DHR+1 h |
PC | 4.0×106 | 1.5 | 24-well | LPS 10 ng/mL | TBARS assay | 24 h |
MGC | 1.5×105 | 1 | 24-well | ConASn 20% | Cytofluorimetry | 30 min DHR+1 h |
Astrocytes | 1.5×105 | 1 | 24-well | ConASn 20% | Cytofluorimetry | 30 min DHR+1 h |
Astrocytes | 0.7×106 | 1.5 | 6-well | ConASn 20% | TBARS assay | 24 h |
Astrocytes | 1.5×105 | 1 | 24-well | ConASn 20% | RT-PCR, immunoblot | 24 h |
C6 cells | 1.5×105 | 1 | 24-well | ConASn 20% | Cytofluorimetry | 30 min DHR+1 h |
C6 cells | 1.5×105 | 1 | 24-well | ConASn 20% | Immunoblot | 24 h |
C6 cells | 1.0×106 | 1.5 | 6-well | ConASn 20% | TBARS assay | 24 h |
SCC | 0.5×106 | 0.2 | 96-well | No | MTT assay, ELISA | 24 h |