Figure 2.

MG-132-induced oxidative stress. (A) ROS was generated in the MG-132-treated (18.5 μmol/L) C6 glioma cells at 3 h, increasing continuously to a peak at 24 h. When tiron (1 mmol/L) was used, ROS generation was blocked (B), and the viability of C6 glioma cells also increased significantly (C). Mean±SD. n=4. ^cP<0.01 vs control group, ^fP<0.01 vs MG-132 group.